Chicken protein combats food pathogens
A protein in the digestive tract of chickens, which
may serve as an antimicrobial agent against food-borne pathogens, has been
identified by Dutch scientists.
Many cases of food poisoning in developed countries are a result of
food-borne pathogens, which are commonly affiliated with poultry products,
particularly chicken. Therapeutic doses of antibiotics have been administered in
chickens, but have been discontinued due to antibiotic resistance.
Research led by Albert van Dijk of Utrecht University tested chickens for
B-defensin gallinacin-6 (Gal-6) protein and explored its antimicrobial activity
against gram-positive and gram-negative bacteria.
High levels of Gal-6 in the chickens' esophagus and crop and moderate
expression in their glandular stomach was observed.
Colony-counting tests showed strong bactericidal activity against various
bacteria, including Campylobacter, Salmonella and E. coli - major food-borne
"To our knowledge, this is the first report of a chicken B-defensin highly
expressed in the digestive tract and displaying strong bactericidal activity
against food-borne pathogens," said the researchers.
This study is reported in the journal "Antimicrobial Agents and
Journal: Antimicrobial Agents and Chemotherapy
PART 2: Significant E. Coli related conditions of
Campylobacter: the state of the art
For the latest
poultry news, subscribe here
To comment, login here
Or register to be able to comment.