Scientists aim to stop Campylobacter infections
Iowa State University scientists are now trying to understand how
Campylobacter develops resistance to antibiotics and is transferred to people
via the food chain causing food-borne illness.
Campylobacter jejuni, associated mainly with poultry, has developed
resistance to fluroquinolone antibiotics after antibiotic treatment of animals.
However, even though these anitobiotics were banned in 2005, the presence of
antibiotic-resistant strains of C. jejuni remained high.
It was discovered that the antibiotic-resistant strains grow more
successfully in the intestinal track of poultry than the non-resistant strain,
even in the absence of antibiotics. The persistence of antibiotic-resistant C.
jejuni in poultry highlights the need for new strategies to control it.
Consequently, researchers are targeting the genes involved in the development
and persistence to prevent emergence and transmission of the antibiotic
"We will continue our efforts to understand the antibiotic resistance
mechanisms and ecology of antibiotic-resistant Campylobacter," said Prof. Qijing
Zhang at I.S.U.* "We are also interested in developing intervention strategies
to prevent the transmission and colonization."
* USDA's Cooperative State Research, Education, and Extension Service
funded this research through the National Research Initiative's Food Safety
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