Lohmann Animal Health’s AviPro® Megan® Egg is a live attenuated Salmonella vaccine specifically developed to protect egg layers against Salmonella Enteritidis infection.
The vaccine reduces the colonization of the intestinal tract and ceca by Salmonella Enteritidis, and is the only commercial live Salmonella vaccine with a claim to protect ovaries and oviducts, says the company.
AviPro® Megan® Egg is for use in pullets and laying hens to protect against infection from Salmonella Enteritidis that is known to contaminate eggs. Pullets generally receive 3 vaccinations during the growing period, providing protection against Salmonella Enteritidis during the laying cycle. AviPro® Megan® Egg is proven to protect hens during molt. It can also be used in a comprehensive Salmonella protection programme in association with inactivated, autogenous Salmonella vaccines, which stimulate the production of long-lasting circulating antibodies.
The vaccine, which is administered through coarse spray vaccination at 2, 4 and 16 weeks of age, is derived from a naturally-occurring Salmonella Typhimurium that has been genetically modified to impair 2 genes that are important for normal growth and metabolism. The modifications to the cya and crp genes result in an organism that is completely distinct from Salmonella species. AviPro® Megan® Egg does not interfere with Salmonella monitoring programs. When cultures are examined using a rapid identification system, the results show a biochemical profile that is considerably distinct from other Salmonella.